Create a new event on sysapproval_approver table and have a related reminder notification. Check event 1 param as recipient check box on the notification.

Use a script like below in the scheduled job and modify as per your need

var queryString = "state=requested^sys_created_on<javascript:gs.daysAgoStart(2)";

var gr = new GlideRecord('sysapproval_approver');

gr.addEncodedQuery(queryString);

gr.query();

while (gr.next()) {

    gs.eventQueue('custom_reminder_event',gr,gr.approver);

}