Thank you @iamkalai, I have used below condition in before query BR on sys_user table, and it works.

Condition: gs.getSession().isInteractive()  && gs.action != ''

Script: if ((gs.action.getGlideURI().toString()).indexOf('impersonate') != -1 || (gs.action.getGlideURI().toString()).indexOf('angular.do?sysparm_type=ref_list_data') != -1) {

  <YOUR CODE GOES HERE>

}

NOTE: Do not add above if condition in the condition field, orelse you will get java null pointer exception while updating record in sys_user table.