Yes. That's called 'inbound action' or 'inbound email flow'. But you are sharing absolutely no information on what you are trying to do, so please update your question with something we can actually provide a useful answer to. This is a 'yes/no' question, and with ServiceNow, it's almost always 'yes' (which could be followed by 'but the question is if you should').
Please mark any helpful or correct solutions as such. That helps others find their solutions.
Mark
